2l81
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2l81 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l81 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2l81 RCSB], [http://www.ebi.ac.uk/pdbsum/2l81 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2l81 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l81 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2l81 RCSB], [http://www.ebi.ac.uk/pdbsum/2l81 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/CASL_HUMAN CASL_HUMAN]] Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B- and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Acton, T B | + | [[Category: Acton, T B]] |
- | [[Category: Ciccosanti, C T | + | [[Category: Ciccosanti, C T]] |
- | [[Category: Everett, J T | + | [[Category: Everett, J T]] |
- | [[Category: Huang, Y J | + | [[Category: Huang, Y J]] |
- | [[Category: Liu, G | + | [[Category: Liu, G]] |
- | [[Category: Montelione, G T | + | [[Category: Montelione, G T]] |
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[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
+ | [[Category: Patel, D]] | ||
+ | [[Category: Tong, S]] | ||
+ | [[Category: Xiao, R]] | ||
+ | [[Category: Cell adhesion]] | ||
+ | [[Category: PSI, Protein structure initiative]] |
Revision as of 15:07, 25 December 2014
Solution NMR Structure of the serine-rich domain of hEF1 (Enhancer of filamentation 1) from Homo sapiens, Northeast Structural Genomics Consortium Target HR5554A
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