3er0
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3er0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ER0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ER0 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3er0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ER0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ER0 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HYP2, TIF51A, YEL034W, SYGP-ORF21 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HYP2, TIF51A, YEL034W, SYGP-ORF21 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3er0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3er0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3er0 RCSB], [http://www.ebi.ac.uk/pdbsum/3er0 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3er0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3er0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3er0 RCSB], [http://www.ebi.ac.uk/pdbsum/3er0 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/IF5A2_YEAST IF5A2_YEAST]] mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Essential for polarized growth, a process necessary for G1/S transition. May mediate large range of effects of the polyamine spermidine in the cell (By similarity).<ref>PMID:641056</ref> <ref>PMID:8307948</ref> <ref>PMID:19338753</ref> <ref>PMID:19424157</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Eukaryotic initiation factor|Eukaryotic initiation factor]] | *[[Eukaryotic initiation factor|Eukaryotic initiation factor]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Aponi, L H | + | [[Category: Aponi, L H]] |
| - | [[Category: Dias, C A.O | + | [[Category: Dias, C A.O]] |
| - | [[Category: Guimaraes, B | + | [[Category: Guimaraes, B]] |
| - | [[Category: Sanches, M | + | [[Category: Sanches, M]] |
| - | [[Category: Valentini, S R | + | [[Category: Valentini, S R]] |
[[Category: Hypusine]] | [[Category: Hypusine]] | ||
[[Category: Initiation factor]] | [[Category: Initiation factor]] | ||
Revision as of 15:07, 25 December 2014
Crystal structure of the full length eIF5A from Saccharomyces cerevisiae
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