2hio

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2hio]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HIO FirstGlance]. <br>
<table><tr><td colspan='2'>[[2hio]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HIO FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hio|1hio]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hio|1hio]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hio RCSB], [http://www.ebi.ac.uk/pdbsum/2hio PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hio OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hio RCSB], [http://www.ebi.ac.uk/pdbsum/2hio PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/H4_CHICK H4_CHICK]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H2A4_CHICK H2A4_CHICK]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Arents, G.]]
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[[Category: Arents, G]]
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[[Category: Moudrianakis, E N.]]
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[[Category: Moudrianakis, E N]]
[[Category: Chromosomal protein]]
[[Category: Chromosomal protein]]
[[Category: Dna binding protein]]
[[Category: Dna binding protein]]
[[Category: Histone]]
[[Category: Histone]]
[[Category: Structural protein]]
[[Category: Structural protein]]

Revision as of 15:08, 25 December 2014

HISTONE OCTAMER (CHICKEN), CHROMOSOMAL PROTEIN

2hio, resolution 3.10Å

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