4lg7
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lg7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lg7 RCSB], [http://www.ebi.ac.uk/pdbsum/4lg7 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lg7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lg7 RCSB], [http://www.ebi.ac.uk/pdbsum/4lg7 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MBD4_HUMAN MBD4_HUMAN]] Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.<ref>PMID:10097147</ref> <ref>PMID:10930409</ref> | ||
==See Also== | ==See Also== | ||
*[[Methyl CpG binding protein|Methyl CpG binding protein]] | *[[Methyl CpG binding protein|Methyl CpG binding protein]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 15:12, 25 December 2014
Crystal structure MBD4 MBD domain in complex with methylated CpG DNA
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