1m8x
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1m8x]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M8X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M8X FirstGlance]. <br> | <table><tr><td colspan='2'>[[1m8x]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M8X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M8X FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ib3|1ib3]], [[1ib2|1ib2]], [[1m8w|1m8w]], [[1m8y|1m8y]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ib3|1ib3]], [[1ib2|1ib2]], [[1m8w|1m8w]], [[1m8y|1m8y]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m8x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m8x RCSB], [http://www.ebi.ac.uk/pdbsum/1m8x PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m8x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m8x RCSB], [http://www.ebi.ac.uk/pdbsum/1m8x PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PUM1_HUMAN PUM1_HUMAN]] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Hall, T M.T | + | [[Category: Hall, T M.T]] |
| - | [[Category: McLachlan, J | + | [[Category: McLachlan, J]] |
| - | [[Category: Wang, X | + | [[Category: Wang, X]] |
| - | [[Category: Zamore, P D | + | [[Category: Zamore, P D]] |
[[Category: Nanos response element]] | [[Category: Nanos response element]] | ||
[[Category: Puf domain]] | [[Category: Puf domain]] | ||
[[Category: Pumilio-homology domain]] | [[Category: Pumilio-homology domain]] | ||
[[Category: Rna binding protein-rna complex]] | [[Category: Rna binding protein-rna complex]] | ||
Revision as of 15:14, 25 December 2014
CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE1-14 RNA
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