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2oqd
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2oqd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bothrops_jararacussu Bothrops jararacussu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OQD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OQD FirstGlance]. <br> | <table><tr><td colspan='2'>[[2oqd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bothrops_jararacussu Bothrops jararacussu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OQD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OQD FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gmz|1gmz]], [[1u73|1u73]], [[1pao|1pao]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gmz|1gmz]], [[1u73|1u73]], [[1pao|1pao]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oqd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2oqd RCSB], [http://www.ebi.ac.uk/pdbsum/2oqd PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oqd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2oqd RCSB], [http://www.ebi.ac.uk/pdbsum/2oqd PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PA21B_BOTJR PA21B_BOTJR]] Snake venom phospholipase A2 (PLA2) that shows a moderate enzymatic activity. It induces indirect hemolytic, anticoagulant, and cytotoxic activities. In vivo, it induces muscle necrosis, accompanied by polymorphonuclear cell infiltration, and edema in the mouse paw. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.<ref>PMID:9619591</ref> <ref>PMID:11018293</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Bothrops jararacussu]] | [[Category: Bothrops jararacussu]] | ||
| - | [[Category: Cintra, A C.O | + | [[Category: Cintra, A C.O]] |
| - | [[Category: Correa, L C | + | [[Category: Correa, L C]] |
| - | [[Category: Fontes, M R.M | + | [[Category: Fontes, M R.M]] |
| - | [[Category: Marchi-Salvador, D P | + | [[Category: Marchi-Salvador, D P]] |
| - | [[Category: Soares, A M | + | [[Category: Soares, A M]] |
[[Category: Asp49-phospholipase a2]] | [[Category: Asp49-phospholipase a2]] | ||
| - | [[Category: Bothrops jararacussu]] | ||
[[Category: Bothropstoxin ii]] | [[Category: Bothropstoxin ii]] | ||
[[Category: Bthtx-ii]] | [[Category: Bthtx-ii]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 15:22, 25 December 2014
Crystal Structure of BthTX-II
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