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1z56

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1z56]] is a 11 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z56 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z56 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1z56]] is a 11 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z56 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z56 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LIF1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae]), DNL4, LIG4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LIF1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae]), DNL4, LIG4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(ATP) DNA ligase (ATP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.1 6.5.1.1] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(ATP) DNA ligase (ATP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.1 6.5.1.1] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z56 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z56 RCSB], [http://www.ebi.ac.uk/pdbsum/1z56 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z56 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z56 RCSB], [http://www.ebi.ac.uk/pdbsum/1z56 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DNL4_YEAST DNL4_YEAST]] Has minor DNA joining activity. Can act on oligo(PDT)/poly(rA) substrate. [[http://www.uniprot.org/uniprot/LIF1_YEAST LIF1_YEAST]] Stabilizes DNL4. Involved in non-homologous repair of DNA double-strand breaks.<ref>PMID:9670033</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Blundell, T L.]]
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[[Category: Blundell, T L]]
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[[Category: Chirgadze, D Y.]]
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[[Category: Chirgadze, D Y]]
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[[Category: Davies, O R.]]
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[[Category: Davies, O R]]
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[[Category: Dore, A S.]]
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[[Category: Dore, A S]]
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[[Category: Furnham, N.]]
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[[Category: Furnham, N]]
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[[Category: Jackson, S P.]]
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[[Category: Jackson, S P]]
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[[Category: Pellegrini, L.]]
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[[Category: Pellegrini, L]]
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[[Category: Sibanda, B L.]]
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[[Category: Sibanda, B L]]
[[Category: Brct]]
[[Category: Brct]]
[[Category: Coiled-coil]]
[[Category: Coiled-coil]]

Revision as of 15:25, 25 December 2014

Co-Crystal Structure of Lif1p-Lig4p

1z56, resolution 3.92Å

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