2xq3

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xq3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xq3 RCSB], [http://www.ebi.ac.uk/pdbsum/2xq3 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xq3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xq3 RCSB], [http://www.ebi.ac.uk/pdbsum/2xq3 PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/Q7NDN8_GLOVI Q7NDN8_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Gloeobacter violaceus pcc 7421]]
[[Category: Gloeobacter violaceus pcc 7421]]
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[[Category: Bertozzi, C.]]
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[[Category: Bertozzi, C]]
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[[Category: Dutzler, R.]]
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[[Category: Dutzler, R]]
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[[Category: Hilf, R J.C.]]
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[[Category: Hilf, R J.C]]
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[[Category: Reiter, A.]]
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[[Category: Reiter, A]]
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[[Category: Trauner, D.]]
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[[Category: Trauner, D]]
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[[Category: Zimmermann, I.]]
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[[Category: Zimmermann, I]]
[[Category: Membrane protein]]
[[Category: Membrane protein]]
[[Category: Open channel block]]
[[Category: Open channel block]]

Revision as of 15:26, 25 December 2014

PENTAMERIC LIGAND GATED ION CHANNEL GLIC IN COMPLEX WITH BR-LIDOCAINE

2xq3, resolution 3.50Å

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