4niq
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4niq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NIQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NIQ FirstGlance]. <br> | <table><tr><td colspan='2'>[[4niq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NIQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NIQ FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CSC1, DID6, END13, GRD13, P9705.10, VPL4, VPS4, VPT10, YPR173C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), SYGP-ORF44, VFA1, YER128W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CSC1, DID6, END13, GRD13, P9705.10, VPL4, VPS4, VPT10, YPR173C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), SYGP-ORF44, VFA1, YER128W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4niq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4niq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4niq RCSB], [http://www.ebi.ac.uk/pdbsum/4niq PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4niq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4niq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4niq RCSB], [http://www.ebi.ac.uk/pdbsum/4niq PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/VPS4_YEAST VPS4_YEAST]] Involved in the transport of biosynthetic membrane proteins from the prevacuolar/endosomal compartment to the vacuole. Required for multivesicular body (MVB) protein sorting. Catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes, such as the disassembly of the ESCRT-III complex.<ref>PMID:11329380</ref> <ref>PMID:9155008</ref> <ref>PMID:9606181</ref> [[http://www.uniprot.org/uniprot/VFA1_YEAST VFA1_YEAST]] VPS4-associated protein involved in trafficking to the vacuole. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Vfa1 Binds to the N-terminal Microtubule-interacting and Trafficking (MIT) Domain of Vps4 and Stimulates Its ATPase Activity.,Vild CJ, Xu Z J Biol Chem. 2014 Apr 11;289(15):10378-86. doi: 10.1074/jbc.M113.532960. Epub, 2014 Feb 24. PMID:24567329<ref>PMID:24567329</ref> | Vfa1 Binds to the N-terminal Microtubule-interacting and Trafficking (MIT) Domain of Vps4 and Stimulates Its ATPase Activity.,Vild CJ, Xu Z J Biol Chem. 2014 Apr 11;289(15):10378-86. doi: 10.1074/jbc.M113.532960. Epub, 2014 Feb 24. PMID:24567329<ref>PMID:24567329</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Baker's yeast]] | [[Category: Baker's yeast]] | ||
| - | [[Category: Vild, C J | + | [[Category: Vild, C J]] |
| - | [[Category: Xu, Z | + | [[Category: Xu, Z]] |
[[Category: Cytosol]] | [[Category: Cytosol]] | ||
[[Category: Protein transport]] | [[Category: Protein transport]] | ||
Revision as of 15:28, 25 December 2014
Crystal Structure of Vps4 MIT-Vfa1 MIM2
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