2yzk

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2yzk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YZK FirstGlance]. <br>
<table><tr><td colspan='2'>[[2yzk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YZK FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yzk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yzk RCSB], [http://www.ebi.ac.uk/pdbsum/2yzk PDBsum], [http://www.topsan.org/Proteins/RSGI/2yzk TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yzk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yzk RCSB], [http://www.ebi.ac.uk/pdbsum/2yzk PDBsum], [http://www.topsan.org/Proteins/RSGI/2yzk TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PYRE_AERPE PYRE_AERPE]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Aeropyrum pernix]]
[[Category: Aeropyrum pernix]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Orotate phosphoribosyltransferase]]
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[[Category: Baba, S.]]
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[[Category: Baba, S]]
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[[Category: Kanagawa, M.]]
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[[Category: Kanagawa, M]]
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[[Category: Kawai, G.]]
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[[Category: Kawai, G]]
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[[Category: Kuramitsu, S.]]
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[[Category: Kuramitsu, S]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Sampei, G.]]
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[[Category: Sampei, G]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama, S]]
[[Category: Glycosyltransferase]]
[[Category: Glycosyltransferase]]
[[Category: Magnesium]]
[[Category: Magnesium]]
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[[Category: Nppsfa]]
[[Category: Nppsfa]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Pyrimidine biosynthesis]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Rossmann fold]]
[[Category: Rossmann fold]]
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 15:36, 25 December 2014

Crystal structure of orotate phosphoribosyltransferase from Aeropyrum pernix

2yzk, resolution 1.80Å

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