This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2yzk
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2yzk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YZK FirstGlance]. <br> | <table><tr><td colspan='2'>[[2yzk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YZK FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yzk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yzk RCSB], [http://www.ebi.ac.uk/pdbsum/2yzk PDBsum], [http://www.topsan.org/Proteins/RSGI/2yzk TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yzk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yzk RCSB], [http://www.ebi.ac.uk/pdbsum/2yzk PDBsum], [http://www.topsan.org/Proteins/RSGI/2yzk TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PYRE_AERPE PYRE_AERPE]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 25: | Line 27: | ||
[[Category: Aeropyrum pernix]] | [[Category: Aeropyrum pernix]] | ||
[[Category: Orotate phosphoribosyltransferase]] | [[Category: Orotate phosphoribosyltransferase]] | ||
| - | [[Category: Baba, S | + | [[Category: Baba, S]] |
| - | [[Category: Kanagawa, M | + | [[Category: Kanagawa, M]] |
| - | [[Category: Kawai, G | + | [[Category: Kawai, G]] |
| - | [[Category: Kuramitsu, S | + | [[Category: Kuramitsu, S]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Sampei, G | + | [[Category: Sampei, G]] |
| - | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: Glycosyltransferase]] | [[Category: Glycosyltransferase]] | ||
[[Category: Magnesium]] | [[Category: Magnesium]] | ||
| Line 37: | Line 39: | ||
[[Category: Nppsfa]] | [[Category: Nppsfa]] | ||
[[Category: Pyrimidine biosynthesis]] | [[Category: Pyrimidine biosynthesis]] | ||
| - | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rossmann fold]] | [[Category: Rossmann fold]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 15:36, 25 December 2014
Crystal structure of orotate phosphoribosyltransferase from Aeropyrum pernix
| |||||||||||
Categories: Aeropyrum pernix | Orotate phosphoribosyltransferase | Baba, S | Kanagawa, M | Kawai, G | Kuramitsu, S | Structural genomic | Sampei, G | Yokoyama, S | Glycosyltransferase | Magnesium | National project on protein structural and functional analyse | Nppsfa | Pyrimidine biosynthesis | Rossmann fold | Rsgi | Transferase
