This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4igz
From Proteopedia
(Difference between revisions)
| Line 7: | Line 7: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4igz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4igz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4igz RCSB], [http://www.ebi.ac.uk/pdbsum/4igz PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4igz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4igz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4igz RCSB], [http://www.ebi.ac.uk/pdbsum/4igz PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SRBS2_HUMAN SRBS2_HUMAN]] Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.<ref>PMID:9211900</ref> <ref>PMID:12475393</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 15:37, 25 December 2014
Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
| |||||||||||
Categories: Homo sapiens | Arrowsmith, C H | Bakkouri, M El | Bountra, C | Edwards, A M | Gu, J | Huang, H | Liu, K | Liu, Y | Min, J | Structural genomic | Sidhu, S S | Tempel, W | Protein binding | Sgc | Sh3 | Src homology 3 domain
