3mvb
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mvb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mvb RCSB], [http://www.ebi.ac.uk/pdbsum/3mvb PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mvb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mvb RCSB], [http://www.ebi.ac.uk/pdbsum/3mvb PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MTERF_HUMAN MTERF_HUMAN]] Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Probably requires one or more components for termination activity.<ref>PMID:20550934</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 15:42, 25 December 2014
Crystal structure of a triple RFY mutant of human MTERF1 bound to the termination sequence
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