3zv8

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zv8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zv8 RCSB], [http://www.ebi.ac.uk/pdbsum/3zv8 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zv8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zv8 RCSB], [http://www.ebi.ac.uk/pdbsum/3zv8 PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/A1E4A3_9ENTO A1E4A3_9ENTO]] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS000199_004_016611] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 15:49, 25 December 2014

Crystal structure of 3C protease of Enterovirus 68

3zv8, resolution 2.40Å

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