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2e6i

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[[Image:2e6i.jpg|left|200px]]<br /><applet load="2e6i" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2e6i.jpg|left|200px]]
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caption="2e6i" />
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'''Solution structure of the BTK motif of tyrosine-protein kinase ITK from human'''<br />
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{{Structure
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|PDB= 2e6i |SIZE=350|CAPTION= <scene name='initialview01'>2e6i</scene>
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|SITE=
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|LIGAND= <scene name='pdbligand=ZN:ZINC ION'>ZN</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2]
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|GENE= ITK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Solution structure of the BTK motif of tyrosine-protein kinase ITK from human'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2E6I is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6I OCA].
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2E6I is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6I OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: ZN]]
[[Category: ZN]]
[[Category: btk]]
[[Category: btk]]
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[[Category: national project on protein structural and functional analyses]]
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[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: rsgi]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
[[Category: tyrosine-protein kinase itk/tsk]]
[[Category: tyrosine-protein kinase itk/tsk]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:06:33 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:36:04 2008''

Revision as of 14:36, 20 March 2008


PDB ID 2e6i

Drag the structure with the mouse to rotate
Ligands:
Gene: ITK (Homo sapiens)
Activity: Non-specific protein-tyrosine kinase, with EC number 2.7.10.2
Coordinates: save as pdb, mmCIF, xml



Solution structure of the BTK motif of tyrosine-protein kinase ITK from human


Disease

Known disease associated with this structure: Polyhydramnios, megalencephaly, and symptomatic epilepsy OMIM:[608626]

About this Structure

2E6I is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 16:36:04 2008

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