4liy
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4liy]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LIY FirstGlance]. <br> | <table><tr><td colspan='2'>[[4liy]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LIY FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1h7z|1h7z]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1h7z|1h7z]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4liy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4liy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4liy RCSB], [http://www.ebi.ac.uk/pdbsum/4liy PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4liy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4liy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4liy RCSB], [http://www.ebi.ac.uk/pdbsum/4liy PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SPIKE_ADE03 SPIKE_ADE03]] Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CD46 to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface. Heparan sulfate might also play a role in virus binding. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 13: | Line 15: | ||
Structural and functional studies on the interaction of adenovirus fiber knobs and desmoglein 2.,Wang H, Yumul R, Cao H, Ran L, Fan X, Richter M, Epstein F, Gralow J, Zubieta C, Fender P, Lieber A J Virol. 2013 Nov;87(21):11346-62. doi: 10.1128/JVI.01825-13. Epub 2013 Aug 14. PMID:23946456<ref>PMID:23946456</ref> | Structural and functional studies on the interaction of adenovirus fiber knobs and desmoglein 2.,Wang H, Yumul R, Cao H, Ran L, Fan X, Richter M, Epstein F, Gralow J, Zubieta C, Fender P, Lieber A J Virol. 2013 Nov;87(21):11346-62. doi: 10.1128/JVI.01825-13. Epub 2013 Aug 14. PMID:23946456<ref>PMID:23946456</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
| Line 19: | Line 21: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Fender, P | + | [[Category: Fender, P]] |
| - | [[Category: Zubieta, C | + | [[Category: Zubieta, C]] |
[[Category: Adenovirus fibre protein knob domain]] | [[Category: Adenovirus fibre protein knob domain]] | ||
[[Category: Desmoglein 2]] | [[Category: Desmoglein 2]] | ||
Revision as of 16:08, 25 December 2014
Structure of the adenovirus 3 knob domain K217E and F224S mutant
| |||||||||||
