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3cf6
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cf6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cf6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cf6 RCSB], [http://www.ebi.ac.uk/pdbsum/3cf6 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cf6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cf6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cf6 RCSB], [http://www.ebi.ac.uk/pdbsum/3cf6 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RAP1B_HUMAN RAP1B_HUMAN]] GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction.<ref>PMID:20332120</ref> <ref>PMID:18660803</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Human]] | [[Category: Human]] | ||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
| - | [[Category: Arias-Palomo, E | + | [[Category: Arias-Palomo, E]] |
| - | [[Category: Bos, J L | + | [[Category: Bos, J L]] |
| - | [[Category: Hadders, M A | + | [[Category: Hadders, M A]] |
| - | [[Category: Llorca, O | + | [[Category: Llorca, O]] |
| - | [[Category: Rehmann, H | + | [[Category: Rehmann, H]] |
| - | [[Category: Schwede, F | + | [[Category: Schwede, F]] |
[[Category: Camp]] | [[Category: Camp]] | ||
[[Category: Epac]] | [[Category: Epac]] | ||
Revision as of 16:11, 25 December 2014
Structure of Epac2 in complex with cyclic-AMP and Rap
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Categories: Human | Lk3 transgenic mice | Arias-Palomo, E | Bos, J L | Hadders, M A | Llorca, O | Rehmann, H | Schwede, F | Camp | Epac | G-protein | Gef | Gtp-binding | Gunanine nucleotide exchange factor | Nucleotide-binding | Rap | Rap1b | Rapgef4 | Signaling protein regulator-gtp-binding protein complex | Signaling protein-gtp-binding protein complex | Sp-camp
