2l1u
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2l1u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l1u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2l1u RCSB], [http://www.ebi.ac.uk/pdbsum/2l1u PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2l1u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l1u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2l1u RCSB], [http://www.ebi.ac.uk/pdbsum/2l1u PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MSRB2_MOUSE MSRB2_MOUSE]] Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance.<ref>PMID:14699060</ref> <ref>PMID:23911929</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Aachmann, F L | + | [[Category: Aachmann, F L]] |
| - | [[Category: Conte, R Del | + | [[Category: Conte, R Del]] |
| - | [[Category: Dikiy, A | + | [[Category: Dikiy, A]] |
| - | [[Category: Gladyshev, V N | + | [[Category: Gladyshev, V N]] |
| - | [[Category: Kim, H | + | [[Category: Kim, H]] |
| - | [[Category: Kwak, G | + | [[Category: Kwak, G]] |
[[Category: Methionine sulfoxide reductase]] | [[Category: Methionine sulfoxide reductase]] | ||
[[Category: Msrb]] | [[Category: Msrb]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Revision as of 16:22, 25 December 2014
Structure-Functional Analysis of Mammalian MsrB2 protein
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