1rzk
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1rzk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RZK FirstGlance]. <br> | <table><tr><td colspan='2'>[[1rzk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RZK FirstGlance]. <br> | ||
- | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr> |
- | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g9n|1g9n]], [[1rz7|1rz7]], [[1rz8|1rz8]], [[1rzf|1rzf]], [[1rzg|1rzg]], [[1rzi|1rzi]], [[1rzj|1rzj]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g9n|1g9n]], [[1rz7|1rz7]], [[1rz8|1rz8]], [[1rzf|1rzf]], [[1rzg|1rzg]], [[1rzi|1rzi]], [[1rzj|1rzj]]</td></tr> |
- | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rzk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rzk RCSB], [http://www.ebi.ac.uk/pdbsum/1rzk PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rzk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rzk RCSB], [http://www.ebi.ac.uk/pdbsum/1rzk PDBsum]</span></td></tr> |
- | <table> | + | </table> |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN]] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
- | [[Category: Choe, H | + | [[Category: Choe, H]] |
- | [[Category: Dimitrov, D S | + | [[Category: Dimitrov, D S]] |
- | [[Category: Farzan, M | + | [[Category: Farzan, M]] |
- | [[Category: Hendrickson, W A | + | [[Category: Hendrickson, W A]] |
- | [[Category: Huang, C C | + | [[Category: Huang, C C]] |
- | [[Category: Kwong, P D | + | [[Category: Kwong, P D]] |
- | [[Category: Majeed, S | + | [[Category: Majeed, S]] |
- | [[Category: Moore, M J | + | [[Category: Moore, M J]] |
- | [[Category: Phogat, S | + | [[Category: Phogat, S]] |
- | [[Category: Robinson, J | + | [[Category: Robinson, J]] |
- | [[Category: Sodroski, J | + | [[Category: Sodroski, J]] |
- | [[Category: Venturi, M | + | [[Category: Venturi, M]] |
- | [[Category: Wyatt, R | + | [[Category: Wyatt, R]] |
- | [[Category: Zhang, M Y | + | [[Category: Zhang, M Y]] |
[[Category: Antigen-binding fragment of human immunoglobulin 17b]] | [[Category: Antigen-binding fragment of human immunoglobulin 17b]] | ||
[[Category: Hiv-1 exterior envelope gp120 from laboratory-adapted isolate]] | [[Category: Hiv-1 exterior envelope gp120 from laboratory-adapted isolate]] |
Revision as of 16:23, 25 December 2014
HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
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Categories: Homo sapiens | Human immunodeficiency virus 1 | Choe, H | Dimitrov, D S | Farzan, M | Hendrickson, W A | Huang, C C | Kwong, P D | Majeed, S | Moore, M J | Phogat, S | Robinson, J | Sodroski, J | Venturi, M | Wyatt, R | Zhang, M Y | Antigen-binding fragment of human immunoglobulin 17b | Hiv-1 exterior envelope gp120 from laboratory-adapted isolate | Hxbc2 | Surface t-cell glycoprotein cd4 | Viral protein-immune system complex