1rzk

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1rzk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RZK FirstGlance]. <br>
<table><tr><td colspan='2'>[[1rzk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RZK FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g9n|1g9n]], [[1rz7|1rz7]], [[1rz8|1rz8]], [[1rzf|1rzf]], [[1rzg|1rzg]], [[1rzi|1rzi]], [[1rzj|1rzj]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g9n|1g9n]], [[1rz7|1rz7]], [[1rz8|1rz8]], [[1rzf|1rzf]], [[1rzg|1rzg]], [[1rzi|1rzi]], [[1rzj|1rzj]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rzk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rzk RCSB], [http://www.ebi.ac.uk/pdbsum/1rzk PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rzk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rzk RCSB], [http://www.ebi.ac.uk/pdbsum/1rzk PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN]] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Choe, H.]]
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[[Category: Choe, H]]
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[[Category: Dimitrov, D S.]]
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[[Category: Dimitrov, D S]]
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[[Category: Farzan, M.]]
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[[Category: Farzan, M]]
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[[Category: Hendrickson, W A.]]
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[[Category: Hendrickson, W A]]
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[[Category: Huang, C C.]]
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[[Category: Huang, C C]]
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[[Category: Kwong, P D.]]
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[[Category: Kwong, P D]]
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[[Category: Majeed, S.]]
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[[Category: Majeed, S]]
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[[Category: Moore, M J.]]
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[[Category: Moore, M J]]
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[[Category: Phogat, S.]]
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[[Category: Phogat, S]]
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[[Category: Robinson, J.]]
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[[Category: Robinson, J]]
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[[Category: Sodroski, J.]]
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[[Category: Sodroski, J]]
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[[Category: Venturi, M.]]
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[[Category: Venturi, M]]
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[[Category: Wyatt, R.]]
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[[Category: Wyatt, R]]
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[[Category: Zhang, M Y.]]
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[[Category: Zhang, M Y]]
[[Category: Antigen-binding fragment of human immunoglobulin 17b]]
[[Category: Antigen-binding fragment of human immunoglobulin 17b]]
[[Category: Hiv-1 exterior envelope gp120 from laboratory-adapted isolate]]
[[Category: Hiv-1 exterior envelope gp120 from laboratory-adapted isolate]]

Revision as of 16:23, 25 December 2014

HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B

1rzk, resolution 2.90Å

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