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2edh
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2edh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EDH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EDH FirstGlance]. <br> | <table><tr><td colspan='2'>[[2edh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EDH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EDH FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OBSCN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OBSCN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2edh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2edh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2edh RCSB], [http://www.ebi.ac.uk/pdbsum/2edh PDBsum], [http://www.topsan.org/Proteins/RSGI/2edh TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2edh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2edh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2edh RCSB], [http://www.ebi.ac.uk/pdbsum/2edh PDBsum], [http://www.topsan.org/Proteins/RSGI/2edh TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/OBSCN_HUMAN OBSCN_HUMAN]] Involved in myofibrillogenesis. Seems to be involved in assembly of myosin into sarcomeric A bands in striated muscle. Isoform 3 together with ANK1 isoform Mu17/Ank1.5 may provide a molecular link between the sarcoplasmic reticulum and myofibrils.<ref>PMID:11448995</ref> <ref>PMID:16205939</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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*[[Group:MUZIC:Obscurin|MUZIC:Obscurin]] | *[[Group:MUZIC:Obscurin|MUZIC:Obscurin]] | ||
*[[Obscurin|Obscurin]] | *[[Obscurin|Obscurin]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Endo, H | + | [[Category: Endo, H]] |
| - | [[Category: Hayashi, F | + | [[Category: Hayashi, F]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
| - | [[Category: Yoshida, M | + | [[Category: Yoshida, M]] |
[[Category: Contractile protein]] | [[Category: Contractile protein]] | ||
[[Category: Ig-fold]] | [[Category: Ig-fold]] | ||
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[[Category: Obscurin-myosin light chain kinase]] | [[Category: Obscurin-myosin light chain kinase]] | ||
[[Category: Obscurin-rhogef]] | [[Category: Obscurin-rhogef]] | ||
| - | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
| - | [[Category: Structural genomic]] | ||
Revision as of 16:35, 25 December 2014
Solution structure of the PDZ domain (3614- 3713 ) from human obscurin
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