2eb8
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:2eb8.jpg|left|200px]] | + | [[Image:2eb8.jpg|left|200px]] |
| - | + | ||
| - | '''Crystal Structure of Cu(II)(Sal-Phe)/apo-Myoglobin''' | + | {{Structure |
| + | |PDB= 2eb8 |SIZE=350|CAPTION= <scene name='initialview01'>2eb8</scene>, resolution 1.65Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=CUP:(N-SALICYLIDEN-L-PHENYLALANATO)-COPPER(II)'>CUP</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''Crystal Structure of Cu(II)(Sal-Phe)/apo-Myoglobin''' | ||
| + | |||
==Overview== | ==Overview== | ||
| Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
| - | 2EB8 is a [ | + | 2EB8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EB8 OCA]. |
==Reference== | ==Reference== | ||
| - | Design and structure analysis of artificial metalloproteins: selective coordination of His64 to copper complexes with square-planar structure in the apo-myoglobin scaffold., Abe S, Ueno T, Reddy PA, Okazaki S, Hikage T, Suzuki A, Yamane T, Nakajima H, Watanabe Y, Inorg Chem. 2007 Jun 25;46(13):5137-9. Epub 2007 May 25. PMID:[http:// | + | Design and structure analysis of artificial metalloproteins: selective coordination of His64 to copper complexes with square-planar structure in the apo-myoglobin scaffold., Abe S, Ueno T, Reddy PA, Okazaki S, Hikage T, Suzuki A, Yamane T, Nakajima H, Watanabe Y, Inorg Chem. 2007 Jun 25;46(13):5137-9. Epub 2007 May 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17523632 17523632] |
[[Category: Physeter catodon]] | [[Category: Physeter catodon]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| Line 24: | Line 33: | ||
[[Category: oxygen storage/transport]] | [[Category: oxygen storage/transport]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:37:45 2008'' |
Revision as of 14:37, 20 March 2008
| |||||||
| , resolution 1.65Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | and | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal Structure of Cu(II)(Sal-Phe)/apo-Myoglobin
Overview
apo-Myoglobin (apo-Mb) was reconstituted with three copper complexes: CuII(Sal-Phe) (1; Sal-Phe = N-salicylidene-L-phenylalanato), CuII(Sal-Leu) (2; Sal-Leu = N-salicylidene-L-leucinato), and CuII(Sal-Ala) (3; Sal-Ala = N-salicylidene-L-alanato). The crystal structures of 1.apo-Mb (1.65 Angstrom resolution) and 2.apo-Mb (1.8 Angstrom resolution) show that the coordination geometry around the CuII atom in apo-Mb is distorted square-planar with tridentate Sal-X and a Nepsilon atom of His64 in the apo-Mb cavity and the plane of these copper complexes is perpendicular to that of heme. These results suggest that the apo-Mb cavity can hold metal complexes with various coordination geometries.
About this Structure
2EB8 is a Single protein structure of sequence from Physeter catodon. Full crystallographic information is available from OCA.
Reference
Design and structure analysis of artificial metalloproteins: selective coordination of His64 to copper complexes with square-planar structure in the apo-myoglobin scaffold., Abe S, Ueno T, Reddy PA, Okazaki S, Hikage T, Suzuki A, Yamane T, Nakajima H, Watanabe Y, Inorg Chem. 2007 Jun 25;46(13):5137-9. Epub 2007 May 25. PMID:17523632
Page seeded by OCA on Thu Mar 20 16:37:45 2008
Categories: Physeter catodon | Single protein | Abe, S. | Hikage, T. | Okazaki, S. | Suzuki, A. | Ueno, T. | Watanabe, Y. | Yamane, T. | CUP | PO4 | Oxygen storage/transport
