3ohv
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3ohv]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OHV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OHV FirstGlance]. <br> | <table><tr><td colspan='2'>[[3ohv]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OHV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OHV FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ohu|3ohu]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ohu|3ohu]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACH2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACH2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ohv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ohv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ohv RCSB], [http://www.ebi.ac.uk/pdbsum/3ohv PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ohv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ohv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ohv RCSB], [http://www.ebi.ac.uk/pdbsum/3ohv PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BACH2_HUMAN BACH2_HUMAN]] Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Play important roles in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1.<ref>PMID:17018862</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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The structure of the Bach2 POZ-domain dimer reveals an intersubunit disulfide bond.,Rosbrook GO, Stead MA, Carr SB, Wright SC Acta Crystallogr D Biol Crystallogr. 2012 Jan;68(Pt 1):26-34. Epub 2011 Dec 9. PMID:22194330<ref>PMID:22194330</ref> | The structure of the Bach2 POZ-domain dimer reveals an intersubunit disulfide bond.,Rosbrook GO, Stead MA, Carr SB, Wright SC Acta Crystallogr D Biol Crystallogr. 2012 Jan;68(Pt 1):26-34. Epub 2011 Dec 9. PMID:22194330<ref>PMID:22194330</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Carr, S B | + | [[Category: Carr, S B]] |
| - | [[Category: Rosbrook, G O | + | [[Category: Rosbrook, G O]] |
| - | [[Category: Stead, M A | + | [[Category: Stead, M A]] |
| - | [[Category: Wright, S C | + | [[Category: Wright, S C]] |
[[Category: Btb/poz domain]] | [[Category: Btb/poz domain]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
Revision as of 16:40, 25 December 2014
Crystal structure of the human Bach2 POZ domain, form II
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