2qgn

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[[Image:2qgn.png|left|200px]]
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==Crystal structure of tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans, Northeast Structural Genomics Consortium target BhR41.==
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<StructureSection load='2qgn' size='340' side='right' caption='[[2qgn]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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{{STRUCTURE_2qgn| PDB=2qgn | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2qgn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans_c-125 Bacillus halodurans c-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QGN FirstGlance]. <br>
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===Crystal structure of tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans, Northeast Structural Genomics Consortium target BhR41.===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">miaA, BH2366 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272558 Bacillus halodurans C-125])</td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_dimethylallyltransferase tRNA dimethylallyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.75 2.5.1.75] </span></td></tr>
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[[2qgn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans_c-125 Bacillus halodurans c-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGN OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qgn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qgn RCSB], [http://www.ebi.ac.uk/pdbsum/2qgn PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MIAA_BACHD MIAA_BACHD]] Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qg/2qgn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Bacillus halodurans c-125]]
[[Category: Bacillus halodurans c-125]]
[[Category: TRNA dimethylallyltransferase]]
[[Category: TRNA dimethylallyltransferase]]
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[[Category: Abashidze, M.]]
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[[Category: Abashidze, M]]
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[[Category: Acton, T B.]]
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[[Category: Acton, T B]]
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[[Category: Baran, M C.]]
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[[Category: Baran, M C]]
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[[Category: Cunningham, K.]]
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[[Category: Cunningham, K]]
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[[Category: Forouhar, F.]]
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[[Category: Forouhar, F]]
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[[Category: Hunt, J F.]]
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[[Category: Hunt, J F]]
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[[Category: Janjua, H.]]
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[[Category: Janjua, H]]
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[[Category: Liu, J.]]
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[[Category: Liu, J]]
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[[Category: Ma, L-C.]]
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[[Category: Ma, L-C]]
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[[Category: Montelione, G T.]]
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[[Category: Montelione, G T]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Neely, H.]]
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[[Category: Neely, H]]
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[[Category: Rost, B.]]
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[[Category: Rost, B]]
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[[Category: Seetharaman, J.]]
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[[Category: Seetharaman, J]]
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[[Category: Shastry, R.]]
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[[Category: Shastry, R]]
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[[Category: Tong, L.]]
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[[Category: Tong, L]]
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[[Category: Xiao, R.]]
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[[Category: Xiao, R]]
[[Category: Alpha-beta protein]]
[[Category: Alpha-beta protein]]
[[Category: Nesg]]
[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 16:41, 25 December 2014

Crystal structure of tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans, Northeast Structural Genomics Consortium target BhR41.

2qgn, resolution 2.40Å

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