2qgn
From Proteopedia
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- | + | ==Crystal structure of tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans, Northeast Structural Genomics Consortium target BhR41.== | |
- | + | <StructureSection load='2qgn' size='340' side='right' caption='[[2qgn]], [[Resolution|resolution]] 2.40Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2qgn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans_c-125 Bacillus halodurans c-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QGN FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
- | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
- | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">miaA, BH2366 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272558 Bacillus halodurans C-125])</td></tr> | |
- | == | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_dimethylallyltransferase tRNA dimethylallyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.75 2.5.1.75] </span></td></tr> |
- | [[2qgn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans_c-125 Bacillus halodurans c-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGN OCA]. | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qgn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qgn RCSB], [http://www.ebi.ac.uk/pdbsum/2qgn PDBsum]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/MIAA_BACHD MIAA_BACHD]] Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A). | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qg/2qgn_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Bacillus halodurans c-125]] | [[Category: Bacillus halodurans c-125]] | ||
[[Category: TRNA dimethylallyltransferase]] | [[Category: TRNA dimethylallyltransferase]] | ||
- | [[Category: Abashidze, M | + | [[Category: Abashidze, M]] |
- | [[Category: Acton, T B | + | [[Category: Acton, T B]] |
- | [[Category: Baran, M C | + | [[Category: Baran, M C]] |
- | [[Category: Cunningham, K | + | [[Category: Cunningham, K]] |
- | [[Category: Forouhar, F | + | [[Category: Forouhar, F]] |
- | [[Category: Hunt, J F | + | [[Category: Hunt, J F]] |
- | [[Category: Janjua, H | + | [[Category: Janjua, H]] |
- | [[Category: Liu, J | + | [[Category: Liu, J]] |
- | [[Category: Ma, L-C | + | [[Category: Ma, L-C]] |
- | [[Category: Montelione, G T | + | [[Category: Montelione, G T]] |
- | [[Category: | + | [[Category: Structural genomic]] |
- | [[Category: Neely, H | + | [[Category: Neely, H]] |
- | [[Category: Rost, B | + | [[Category: Rost, B]] |
- | [[Category: Seetharaman, J | + | [[Category: Seetharaman, J]] |
- | [[Category: Shastry, R | + | [[Category: Shastry, R]] |
- | [[Category: Tong, L | + | [[Category: Tong, L]] |
- | [[Category: Xiao, R | + | [[Category: Xiao, R]] |
[[Category: Alpha-beta protein]] | [[Category: Alpha-beta protein]] | ||
[[Category: Nesg]] | [[Category: Nesg]] | ||
- | [[Category: | + | [[Category: PSI, Protein structure initiative]] |
- | + | ||
- | + | ||
- | + | ||
[[Category: Transferase]] | [[Category: Transferase]] |
Revision as of 16:41, 25 December 2014
Crystal structure of tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans, Northeast Structural Genomics Consortium target BhR41.
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Categories: Bacillus halodurans c-125 | TRNA dimethylallyltransferase | Abashidze, M | Acton, T B | Baran, M C | Cunningham, K | Forouhar, F | Hunt, J F | Janjua, H | Liu, J | Ma, L-C | Montelione, G T | Structural genomic | Neely, H | Rost, B | Seetharaman, J | Shastry, R | Tong, L | Xiao, R | Alpha-beta protein | Nesg | PSI, Protein structure initiative | Transferase