3va2

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3va2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VA2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VA2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3va2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VA2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VA2 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IL5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), IL5RA, IL5R ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IL5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), IL5RA, IL5R ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3va2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3va2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3va2 RCSB], [http://www.ebi.ac.uk/pdbsum/3va2 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3va2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3va2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3va2 RCSB], [http://www.ebi.ac.uk/pdbsum/3va2 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/IL5_HUMAN IL5_HUMAN]] Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. [[http://www.uniprot.org/uniprot/IL5RA_HUMAN IL5RA_HUMAN]] This is the receptor for interleukin-5. The alpha chain binds to IL5.
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Kukimoto-Niino, M.]]
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[[Category: Kukimoto-Niino, M]]
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[[Category: Kusano, S.]]
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[[Category: Kusano, S]]
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[[Category: Shirouzu, M.]]
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[[Category: Shirouzu, M]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama, S]]
[[Category: Asthma]]
[[Category: Asthma]]
[[Category: B cell growth]]
[[Category: B cell growth]]

Revision as of 16:53, 25 December 2014

Crystal structure of human Interleukin-5 in complex with its alpha receptor

3va2, resolution 2.70Å

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