3qve
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qve OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qve RCSB], [http://www.ebi.ac.uk/pdbsum/3qve PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qve OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qve RCSB], [http://www.ebi.ac.uk/pdbsum/3qve PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HBP1_HUMAN HBP1_HUMAN]] Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.<ref>PMID:10958660</ref> <ref>PMID:10562551</ref> <ref>PMID:11500377</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 17:01, 25 December 2014
Crystal structure of human HMG box-containing protein 1, HBP1
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Categories: Homo sapiens | Arrowsmith, C H | Bountra, C | Chaikuad, A | Cocking, R | Structural genomic | Delft, F von | Edwards, A M | Filippakopoulos, P | Krojer, T | Krysztofinska, E | Oppermann, U | Ugochukwu, E | Vollmar, M | Weigelt, J | Yue, W W | Axh domain | Hbp1 | Hmg box transcription factor 1 | Sgc | Transcription
