2gvx

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2gvx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Loligo_vulgaris Loligo vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GVX FirstGlance]. <br>
<table><tr><td colspan='2'>[[2gvx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Loligo_vulgaris Loligo vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GVX FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diisopropyl-fluorophosphatase Diisopropyl-fluorophosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.2 3.1.8.2] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diisopropyl-fluorophosphatase Diisopropyl-fluorophosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.2 3.1.8.2] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gvx RCSB], [http://www.ebi.ac.uk/pdbsum/2gvx PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gvx RCSB], [http://www.ebi.ac.uk/pdbsum/2gvx PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DFPA_LOLVU DFPA_LOLVU]] Biological function and substrate unknown. However, it is capable of acting on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including nerve gases).<ref>PMID:15966726</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Diisopropyl-fluorophosphatase]]
[[Category: Diisopropyl-fluorophosphatase]]
[[Category: Loligo vulgaris]]
[[Category: Loligo vulgaris]]
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[[Category: Blum, M M.]]
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[[Category: Blum, M M]]
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[[Category: Chen, J C.H.]]
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[[Category: Chen, J C.H]]
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[[Category: Lohr, F.]]
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[[Category: Lohr, F]]
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[[Category: Richardt, A.]]
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[[Category: Richardt, A]]
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[[Category: Ruterjans, H.]]
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[[Category: Ruterjans, H]]
[[Category: Beta-propeller]]
[[Category: Beta-propeller]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Phosphotriesterase]]
[[Category: Phosphotriesterase]]

Revision as of 17:01, 25 December 2014

Structure of diisopropyl fluorophosphatase (DFPase), mutant D229N / N175D

2gvx, resolution 2.00Å

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