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4c77
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c77 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c77 RCSB], [http://www.ebi.ac.uk/pdbsum/4c77 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c77 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c77 RCSB], [http://www.ebi.ac.uk/pdbsum/4c77 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PAMO_THEFY PAMO_THEFY]] Catalyzes a Baeyer-Villiger oxidation reaction, i.e. the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Is most efficient with phenylacetone as substrate, leading to the formation of benzyl acetate. Can also oxidize other aromatic ketones (benzylacetone, alpha-methylphenylacetone and 4-hydroxyacetophenone), some aliphatic ketones (dodecan-2-one and bicyclohept-2-en-6-one) and sulfides (e.g. methyl 4-tolylsulfide). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 17:01, 25 December 2014
Phenylacetone monooxygenase: oxidised R337K mutant in complex with APADP
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