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2xot
From Proteopedia
(Difference between revisions)
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<StructureSection load='2xot' size='340' side='right' caption='[[2xot]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='2xot' size='340' side='right' caption='[[2xot]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xot]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XOT OCA]. <br> | + | <table><tr><td colspan='2'>[[2xot]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XOT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XOT FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xot OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xot RCSB], [http://www.ebi.ac.uk/pdbsum/2xot PDBsum]</span></td></tr> | |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xot OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xot RCSB], [http://www.ebi.ac.uk/pdbsum/2xot PDBsum]</span></td></tr> | + | </table> |
| - | <table> | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/AMGO1_MOUSE AMGO1_MOUSE]] Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity).[UniProtKB:Q80ZD7] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Crystal Structure and Role of Glycans and Dimerization in Folding of Neuronal Leucine-Rich Repeat Protein AMIGO-1.,Kajander T, Kuja-Panula J, Rauvala H, Goldman A J Mol Biol. 2011 Nov 11;413(5):1001-15. Epub 2011 Sep 29. PMID:21983541<ref>PMID:21983541</ref> | Crystal Structure and Role of Glycans and Dimerization in Folding of Neuronal Leucine-Rich Repeat Protein AMIGO-1.,Kajander T, Kuja-Panula J, Rauvala H, Goldman A J Mol Biol. 2011 Nov 11;413(5):1001-15. Epub 2011 Sep 29. PMID:21983541<ref>PMID:21983541</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Goldman, A | + | [[Category: Goldman, A]] |
| - | [[Category: Kajander, T | + | [[Category: Kajander, T]] |
| - | [[Category: Kuja-Panula, J | + | [[Category: Kuja-Panula, J]] |
| - | [[Category: Rauvala, H | + | [[Category: Rauvala, H]] |
[[Category: Cell adhesion]] | [[Category: Cell adhesion]] | ||
[[Category: Neurite growth regulation]] | [[Category: Neurite growth regulation]] | ||
[[Category: Neuronal protein]] | [[Category: Neuronal protein]] | ||
Revision as of 17:09, 25 December 2014
CRYSTAL STRUCTURE OF NEURONAL LEUCINE RICH REPEAT PROTEIN AMIGO-1
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