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2g0l
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g0l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g0l RCSB], [http://www.ebi.ac.uk/pdbsum/2g0l PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g0l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g0l RCSB], [http://www.ebi.ac.uk/pdbsum/2g0l PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NCZS_STRCZ NCZS_STRCZ]] NCS has antibiotic activity (for Gram-positive bacteria) and antitumor activity (for certain mouse tumors). NCS binds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic. The chromophore binds to DNA as a weak intercalator and causes single- and double-strand breaks. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Streptomyces carzinostaticus]] | [[Category: Streptomyces carzinostaticus]] | ||
| - | [[Category: Caddick, S | + | [[Category: Caddick, S]] |
| - | [[Category: Muskett, F W | + | [[Category: Muskett, F W]] |
| - | [[Category: Stoneman, R G | + | [[Category: Stoneman, R G]] |
| - | [[Category: Woolfson, D N | + | [[Category: Woolfson, D N]] |
[[Category: Antibiotic]] | [[Category: Antibiotic]] | ||
[[Category: Beta sandwich]] | [[Category: Beta sandwich]] | ||
[[Category: Igg fold]] | [[Category: Igg fold]] | ||
Revision as of 17:21, 25 December 2014
Solution Structure of Neocarzinostatin Apo-Protein with bound Flavone
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