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2ma6

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ma6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ma6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ma6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ma6 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ma6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ma6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ma6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ma6 PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RN123_HUMAN RN123_HUMAN]] Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.<ref>PMID:15531880</ref> <ref>PMID:16227581</ref>
==See Also==
==See Also==
*[[Ubiquitin protein ligase|Ubiquitin protein ligase]]
*[[Ubiquitin protein ligase|Ubiquitin protein ligase]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Revision as of 17:24, 25 December 2014

Solution NMR Structure of the RING finger domain from the Kip1 ubiquitination-promoting E3 complex protein 1 (KPC1/RNF123) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8700A

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