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2dbg

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2dbg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DBG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DBG FirstGlance]. <br>
<table><tr><td colspan='2'>[[2dbg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DBG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DBG FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AB1735_E12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AB1735_E12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dbg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dbg RCSB], [http://www.ebi.ac.uk/pdbsum/2dbg PDBsum], [http://www.topsan.org/Proteins/RSGI/2dbg TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dbg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dbg RCSB], [http://www.ebi.ac.uk/pdbsum/2dbg PDBsum], [http://www.topsan.org/Proteins/RSGI/2dbg TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MNDA_HUMAN MNDA_HUMAN]] May act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Inoue, M.]]
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[[Category: Inoue, M]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa, T]]
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[[Category: Koshiba, S.]]
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[[Category: Koshiba, S]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Saito, K.]]
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[[Category: Saito, K]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama, S]]
[[Category: Dna-binding]]
[[Category: Dna-binding]]
[[Category: Immune system]]
[[Category: Immune system]]
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[[Category: National project on protein structural and functional analyse]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 

Revision as of 17:24, 25 December 2014

Solution structure of the Pyrin (PAAD-DAPIN) domain in human Myeloid cell nuclear differentiation antigen

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