3rl5

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3rl5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RL5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RL5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3rl5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RL5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RL5 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ib7|3ib7]], [[3ib8|3ib8]], [[2hy1|2hy1]], [[2hy0|2hy0]], [[2hyp|2hyp]], [[3rl4|3rl4]], [[3rl3|3rl3]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ib7|3ib7]], [[3ib8|3ib8]], [[2hy1|2hy1]], [[2hy0|2hy0]], [[2hyp|2hyp]], [[3rl4|3rl4]], [[3rl3|3rl3]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mpped2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mpped2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rl5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rl5 RCSB], [http://www.ebi.ac.uk/pdbsum/3rl5 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rl5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rl5 RCSB], [http://www.ebi.ac.uk/pdbsum/3rl5 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MPPD2_RAT MPPD2_RAT]] Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.,Dermol U, Janardan V, Tyagi R, Visweswariah SS, Podobnik M J Mol Biol. 2011 Sep 23;412(3):481-94. Epub 2011 Jul 30. PMID:21824479<ref>PMID:21824479</ref>
Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.,Dermol U, Janardan V, Tyagi R, Visweswariah SS, Podobnik M J Mol Biol. 2011 Sep 23;412(3):481-94. Epub 2011 Jul 30. PMID:21824479<ref>PMID:21824479</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Dermol, U.]]
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[[Category: Dermol, U]]
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[[Category: Podobnik, M.]]
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[[Category: Podobnik, M]]
[[Category: Active site mutant]]
[[Category: Active site mutant]]
[[Category: Alpha-beta fold]]
[[Category: Alpha-beta fold]]

Revision as of 17:29, 25 December 2014

Rat metallophosphodiesterase MPPED2 H67R Mutant

3rl5, resolution 1.26Å

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