2lb7

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<StructureSection load='2lb7' size='340' side='right' caption='[[2lb7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2lb7' size='340' side='right' caption='[[2lb7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2lb7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Triticum_kiharae Triticum kiharae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LB7 OCA]. <br>
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<table><tr><td colspan='2'>[[2lb7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Triticum_kiharae Triticum kiharae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LB7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LB7 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lb7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lb7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lb7 RCSB], [http://www.ebi.ac.uk/pdbsum/2lb7 PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lb7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lb7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lb7 RCSB], [http://www.ebi.ac.uk/pdbsum/2lb7 PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[[http://www.uniprot.org/uniprot/AMP_TRIKH AMP_TRIKH]] Binds chitin. WAMP-1a has antifungal activity against the fungi F.solani (IC(50)=5 ug/ml), F.verticillioides (IC(50)=30 ug/ml), F.oxysporum (IC(50)=5 ug/ml), B.sorokiniana (IC(50)=5 ug/ml), B.cinerea (IC(50)=20 ug/ml) and N.crassa (IC(50)=10 ug/ml). Inhibits hyphal elongation and causes browning of hyphae in F.oxysporum. Causes destruction and discoloration of spores in B.sorokiniana. Inhibits the development of disease caused by the fungus P.infestans on potato tubers. Has antibacterial activity against the Gram-negative bacteria P.syringae and E.carotovora, and the Gram-positive bacterium C.michiganensis.<ref>PMID:19583772</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Solution structure of a defense peptide from wheat with a 10-cysteine motif.,Dubovskii PV, Vassilevski AA, Slavokhotova AA, Odintsova TI, Grishin EV, Egorov TA, Arseniev AS Biochem Biophys Res Commun. 2011 Jul 22;411(1):14-8. Epub 2011 Jun 14. PMID:21704019<ref>PMID:21704019</ref>
Solution structure of a defense peptide from wheat with a 10-cysteine motif.,Dubovskii PV, Vassilevski AA, Slavokhotova AA, Odintsova TI, Grishin EV, Egorov TA, Arseniev AS Biochem Biophys Res Commun. 2011 Jul 22;411(1):14-8. Epub 2011 Jun 14. PMID:21704019<ref>PMID:21704019</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Triticum kiharae]]
[[Category: Triticum kiharae]]
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[[Category: Arseniev, A S.]]
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[[Category: Arseniev, A S]]
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[[Category: Balashova, T A.]]
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[[Category: Balashova, T A]]
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[[Category: Egorov, T A.]]
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[[Category: Egorov, T A]]
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[[Category: Grishin, E V.]]
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[[Category: Grishin, E V]]
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[[Category: Odintsova, T I.]]
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[[Category: Odintsova, T I]]
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[[Category: Vassilevski, A A.]]
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[[Category: Vassilevski, A A]]
[[Category: Antimicrobial protein]]
[[Category: Antimicrobial protein]]

Revision as of 17:32, 25 December 2014

Hevein-type Antifungal Peptide with a Unique 10-Cysteine Motif

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