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1ws5
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ws5]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WS5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WS5 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1ws5]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WS5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WS5 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jac|1jac]], [[1m26|1m26]], [[1ugx|1ugx]], [[1uh1|1uh1]], [[1ugw|1ugw]], [[1ws4|1ws4]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jac|1jac]], [[1m26|1m26]], [[1ugx|1ugx]], [[1uh1|1uh1]], [[1ugw|1ugw]], [[1ws4|1ws4]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ws5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ws5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ws5 RCSB], [http://www.ebi.ac.uk/pdbsum/1ws5 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ws5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ws5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ws5 RCSB], [http://www.ebi.ac.uk/pdbsum/1ws5 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LECA_ARTIN LECA_ARTIN]] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Artocarpus integer]] | [[Category: Artocarpus integer]] | ||
| - | [[Category: Jayashree, G | + | [[Category: Jayashree, G]] |
| - | [[Category: Jeyaprakash, A A | + | [[Category: Jeyaprakash, A A]] |
| - | [[Category: Mahanta, S K | + | [[Category: Mahanta, S K]] |
| - | [[Category: Sekar, K | + | [[Category: Sekar, K]] |
| - | [[Category: Surolia, A | + | [[Category: Surolia, A]] |
| - | [[Category: Vijayan, M | + | [[Category: Vijayan, M]] |
[[Category: Beta-prism-i fold]] | [[Category: Beta-prism-i fold]] | ||
[[Category: Galactose-specific]] | [[Category: Galactose-specific]] | ||
Revision as of 17:34, 25 December 2014
Crystal structure of Jacalin-Me-alpha-Mannose complex: Promiscuity vs Specificity
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