1n4h

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1n4h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N4H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1N4H FirstGlance]. <br>
<table><tr><td colspan='2'>[[1n4h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N4H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1N4H FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=REA:RETINOIC+ACID'>REA</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=REA:RETINOIC+ACID'>REA</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1k4w|1k4w]], [[2lbd|2lbd]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1k4w|1k4w]], [[2lbd|2lbd]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RZR-beta ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RZR-beta ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n4h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1n4h RCSB], [http://www.ebi.ac.uk/pdbsum/1n4h PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n4h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1n4h RCSB], [http://www.ebi.ac.uk/pdbsum/1n4h PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RORB_RAT RORB_RAT]] Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Dorsselaer, A Van.]]
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[[Category: Dorsselaer, A Van]]
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[[Category: Moras, D.]]
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[[Category: Moras, D]]
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[[Category: Renaud, J P.]]
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[[Category: Renaud, J P]]
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[[Category: Sanglier, S.]]
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[[Category: Sanglier, S]]
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[[Category: Schuele, R.]]
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[[Category: Schuele, R]]
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[[Category: Stehlin-Gaon, C.]]
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[[Category: Stehlin-Gaon, C]]
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[[Category: Willmann, D.]]
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[[Category: Willmann, D]]
[[Category: Alpha-helical sandwich]]
[[Category: Alpha-helical sandwich]]
[[Category: Hormone-growth factor complex]]
[[Category: Hormone-growth factor complex]]
[[Category: Protein-peptide-ligand complex]]
[[Category: Protein-peptide-ligand complex]]

Revision as of 17:43, 25 December 2014

Characterization of ligands for the orphan nuclear receptor RORbeta

1n4h, resolution 2.10Å

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