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4i9o
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i9o RCSB], [http://www.ebi.ac.uk/pdbsum/4i9o PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i9o RCSB], [http://www.ebi.ac.uk/pdbsum/4i9o PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CBP_MOUSE CBP_MOUSE]] Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300 (By similarity).<ref>PMID:10207073</ref> <ref>PMID:11701890</ref> <ref>PMID:15220471</ref> <ref>PMID:16287980</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 18:09, 25 December 2014
Crystal Structure of GACKIX L664C Tethered to 1-10
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