3uci
From Proteopedia
(Difference between revisions)
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| - | [[ | + | ==Crystal structure of Rhodostomin ARLDDL mutant== |
| + | <StructureSection load='3uci' size='340' side='right' caption='[[3uci]], [[Resolution|resolution]] 1.35Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3uci]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UCI FirstGlance]. <br> | ||
| + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RHOD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8717 Calloselasma rhodostoma])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uci OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3uci RCSB], [http://www.ebi.ac.uk/pdbsum/3uci PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3). | ||
| - | + | ==See Also== | |
| - | + | *[[Disintegrin|Disintegrin]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | + | ||
| - | [[ | + | |
[[Category: Calloselasma rhodostoma]] | [[Category: Calloselasma rhodostoma]] | ||
| - | [[Category: Chang, Y S | + | [[Category: Chang, Y S]] |
| - | [[Category: Chang, Y T | + | [[Category: Chang, Y T]] |
| - | [[Category: Chen, C Y | + | [[Category: Chen, C Y]] |
| - | [[Category: Chen, Y C | + | [[Category: Chen, Y C]] |
| - | [[Category: Chuang, W J | + | [[Category: Chuang, W J]] |
| - | [[Category: Huang, C H | + | [[Category: Huang, C H]] |
| - | [[Category: Shiu, J H | + | [[Category: Shiu, J H]] |
[[Category: Disintegrin]] | [[Category: Disintegrin]] | ||
[[Category: Integrin alphavbeta3]] | [[Category: Integrin alphavbeta3]] | ||
[[Category: Toxin]] | [[Category: Toxin]] | ||
Revision as of 18:29, 25 December 2014
Crystal structure of Rhodostomin ARLDDL mutant
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