3tw4
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3tw4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TW4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TW4 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3tw4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TW4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TW4 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SEPT7, CDC10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SEPT7, CDC10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tw4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tw4 RCSB], [http://www.ebi.ac.uk/pdbsum/3tw4 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tw4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tw4 RCSB], [http://www.ebi.ac.uk/pdbsum/3tw4 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SEPT7_HUMAN SEPT7_HUMAN]] Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements.<ref>PMID:17803907</ref> <ref>PMID:18460473</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Promiscuous interactions of human septins: The GTP binding domain of SEPT7 forms filaments within the crystal.,Serrao VH, Alessandro F, Caldas VE, Marcal RL, D'Muniz Pereira H, Thiemann OH, Garratt RC FEBS Lett. 2011 Nov 3. PMID:22064074<ref>PMID:22064074</ref> | Promiscuous interactions of human septins: The GTP binding domain of SEPT7 forms filaments within the crystal.,Serrao VH, Alessandro F, Caldas VE, Marcal RL, D'Muniz Pereira H, Thiemann OH, Garratt RC FEBS Lett. 2011 Nov 3. PMID:22064074<ref>PMID:22064074</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Alessandro, F | + | [[Category: Alessandro, F]] |
| - | [[Category: Garratt, R C | + | [[Category: Garratt, R C]] |
| - | [[Category: Pereira, H M | + | [[Category: Pereira, H M]] |
| - | [[Category: Serrao, V H.B | + | [[Category: Serrao, V H.B]] |
[[Category: Thiemann, O T]] | [[Category: Thiemann, O T]] | ||
[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
[[Category: Gtpase]] | [[Category: Gtpase]] | ||
[[Category: Septin]] | [[Category: Septin]] | ||
Revision as of 18:31, 25 December 2014
Crystal Structure of Human Septin 7 GTPase Domain
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