1ys3

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ys3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YS3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ys3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YS3 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ys6|1ys6]], [[1ys7|1ys7]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ys6|1ys6]], [[1ys7|1ys7]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MTB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MTB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ys3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ys3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ys3 RCSB], [http://www.ebi.ac.uk/pdbsum/1ys3 PDBsum], [http://www.topsan.org/Proteins/XMTB/1ys3 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ys3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ys3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ys3 RCSB], [http://www.ebi.ac.uk/pdbsum/1ys3 PDBsum], [http://www.topsan.org/Proteins/XMTB/1ys3 TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PRRB_MYCTU PRRB_MYCTU]] Member of the two-component regulatory system PrrB/PrrA. Involved specifically in early intracellular multiplication of Mycobacterium. Probably phosphorylates PrrA.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Nowak, E.]]
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[[Category: Nowak, E]]
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[[Category: Panjikar, S.]]
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[[Category: Panjikar, S]]
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[[Category: Tucker, P.]]
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[[Category: Tucker, P]]
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[[Category: XMTB, Mycobacterium Tuberculosis Structural Proteomics Project.]]
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[[Category: XMTB, Mycobacterium Tuberculosis Structural Proteomics Project]]
[[Category: Atp-binding domain]]
[[Category: Atp-binding domain]]
[[Category: Histidine kinase]]
[[Category: Histidine kinase]]

Revision as of 18:31, 25 December 2014

Crystal Structure of the ATP binding domain of PrrB from Mycobacterium Tuberculosis

1ys3, resolution 1.90Å

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