3f05
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f05 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3f05 RCSB], [http://www.ebi.ac.uk/pdbsum/3f05 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f05 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3f05 RCSB], [http://www.ebi.ac.uk/pdbsum/3f05 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SYT1_HUMAN SYT1_HUMAN]] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 18:44, 25 December 2014
Crystal Structure of Synaptotagmin I C2A domain with Mn(II)
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