3j5y
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j5y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j5y RCSB], [http://www.ebi.ac.uk/pdbsum/3j5y PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j5y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j5y RCSB], [http://www.ebi.ac.uk/pdbsum/3j5y PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ERF1_HUMAN ERF1_HUMAN]] Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.<ref>PMID:7990965</ref> [[http://www.uniprot.org/uniprot/ERF3A_HUMAN ERF3A_HUMAN]] Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Human]] | [[Category: Human]] | ||
[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
| - | [[Category: Frank, J | + | [[Category: Frank, J]] |
| - | [[Category: Georges, A des | + | [[Category: Georges, A des]] |
| - | [[Category: Grassucci, R A | + | [[Category: Grassucci, R A]] |
| - | [[Category: Hashem, Y | + | [[Category: Hashem, Y]] |
| - | [[Category: Hellen, C U.T | + | [[Category: Hellen, C U.T]] |
| - | [[Category: Pestova, T V | + | [[Category: Pestova, T V]] |
| - | [[Category: Taylor, D | + | [[Category: Taylor, D]] |
| - | [[Category: Unbehaun, A | + | [[Category: Unbehaun, A]] |
[[Category: Erf1]] | [[Category: Erf1]] | ||
[[Category: Erf3]] | [[Category: Erf3]] | ||
Revision as of 18:51, 25 December 2014
Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP
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