3i59

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i59 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i59 RCSB], [http://www.ebi.ac.uk/pdbsum/3i59 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i59 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i59 RCSB], [http://www.ebi.ac.uk/pdbsum/3i59 PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/O69644_MYCTU O69644_MYCTU]] Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites, causing DNA-bending, to regulate transcription. cAMP improves binding to specific DNA sequences, probably by altering protein conformation. Activates expression of whiB1.<ref>PMID:16946269</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 18:51, 25 December 2014

Crystal structure of MtbCRP in complex with N6-cAMP

3i59, resolution 2.29Å

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