3qr2
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3qr2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QR2 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3qr2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QR2 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qqn|3qqn]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qqn|3qqn]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BSG, UNQ6505/PRO21383 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BSG, UNQ6505/PRO21383 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qr2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qr2 RCSB], [http://www.ebi.ac.uk/pdbsum/3qr2 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qr2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qr2 RCSB], [http://www.ebi.ac.uk/pdbsum/3qr2 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BASI_HUMAN BASI_HUMAN]] Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.<ref>PMID:17127621</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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The Retinal Specific CD147 Ig0 Domain: From Molecular Structure to Biological Activity.,Redzic JS, Armstrong GS, Isern NG, Jones DN, Kieft JS, Eisenmesser EZ J Mol Biol. 2011 Aug 5;411(1):68-82. Epub 2011 May 19. PMID:21620857<ref>PMID:21620857</ref> | The Retinal Specific CD147 Ig0 Domain: From Molecular Structure to Biological Activity.,Redzic JS, Armstrong GS, Isern NG, Jones DN, Kieft JS, Eisenmesser EZ J Mol Biol. 2011 Aug 5;411(1):68-82. Epub 2011 May 19. PMID:21620857<ref>PMID:21620857</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Armstrong, G S | + | [[Category: Armstrong, G S]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Eisenmesser, E Z | + | [[Category: Eisenmesser, E Z]] |
| - | [[Category: Isern, N G | + | [[Category: Isern, N G]] |
| - | [[Category: Kieft, J S | + | [[Category: Kieft, J S]] |
| - | [[Category: Redzic, J S | + | [[Category: Redzic, J S]] |
| - | + | ||
[[Category: Beta sheet]] | [[Category: Beta sheet]] | ||
[[Category: Bsgc]] | [[Category: Bsgc]] | ||
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[[Category: Emmprin]] | [[Category: Emmprin]] | ||
[[Category: Immunoglobulin-like domain]] | [[Category: Immunoglobulin-like domain]] | ||
| - | [[Category: Structural genomic]] | ||
Revision as of 18:54, 25 December 2014
Wild type CD147 Ig0 domain
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