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4gku
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gku OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gku RCSB], [http://www.ebi.ac.uk/pdbsum/4gku PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gku OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gku RCSB], [http://www.ebi.ac.uk/pdbsum/4gku PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BLAT_ECOLX BLAT_ECOLX]] TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4 are capable of hydrolyzing cefotaxime and ceftazidime. TEM-5 is capable of hydrolyzing ceftazidime. TEM-6 is capable of hydrolyzing ceftazidime and aztreonam. TEM-8/CAZ-2, TEM-16/CAZ-7 and TEM-24/CAZ-6 are markedly active against ceftazidime. IRT-4 shows resistance to beta-lactamase inhibitors. | ||
==See Also== | ==See Also== | ||
Revision as of 18:55, 25 December 2014
Crystal structure of beta lactamase in PET-15B
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