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3aj4

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3aj4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AJ4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AJ4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3aj4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AJ4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AJ4 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3aj4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aj4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3aj4 RCSB], [http://www.ebi.ac.uk/pdbsum/3aj4 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3aj4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aj4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3aj4 RCSB], [http://www.ebi.ac.uk/pdbsum/3aj4 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PKHB2_HUMAN PKHB2_HUMAN]] Involved in retrograde transport of recycling endosomes.<ref>PMID:21911378</ref> <ref>PMID:22281740</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes.,Uchida Y, Hasegawa J, Chinnapen D, Inoue T, Okazaki S, Kato R, Wakatsuki S, Misaki R, Koike M, Uchiyama Y, Iemura S, Natsume T, Kuwahara R, Nakagawa T, Nishikawa K, Mukai K, Miyoshi E, Taniguchi N, Sheff D, Lencer WI, Taguchi T, Arai H Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15846-51. Epub 2011 Sep 12. PMID:21911378<ref>PMID:21911378</ref>
Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes.,Uchida Y, Hasegawa J, Chinnapen D, Inoue T, Okazaki S, Kato R, Wakatsuki S, Misaki R, Koike M, Uchiyama Y, Iemura S, Natsume T, Kuwahara R, Nakagawa T, Nishikawa K, Mukai K, Miyoshi E, Taniguchi N, Sheff D, Lencer WI, Taguchi T, Arai H Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15846-51. Epub 2011 Sep 12. PMID:21911378<ref>PMID:21911378</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Kato, R.]]
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[[Category: Kato, R]]
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[[Category: Okazaki, S.]]
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[[Category: Okazaki, S]]
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[[Category: Wakatsuki, S.]]
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[[Category: Wakatsuki, S]]
[[Category: Antiparallel beta sheet]]
[[Category: Antiparallel beta sheet]]
[[Category: Protein transport]]
[[Category: Protein transport]]

Revision as of 18:56, 25 December 2014

Crystal structure of the PH domain of Evectin-2 from human complexed with O-phospho-L-serine

3aj4, resolution 1.00Å

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