3i4h

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i4h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i4h RCSB], [http://www.ebi.ac.uk/pdbsum/3i4h PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i4h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i4h RCSB], [http://www.ebi.ac.uk/pdbsum/3i4h PDBsum]</span></td></tr>
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== Function ==
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[[http://www.uniprot.org/uniprot/Q8U1S4_PYRFU Q8U1S4_PYRFU]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA), also called psiRNA (prokaryotic silencing) in this organism. Processes pre-crRNA into individual crRNA units, with an 8-nt 5'-repeat DNA tag that may help other proteins recognize the crRNA. Further processing occurs at their 3' termini in this organism. Generates a 5' hydroxy and 2',3'-cyclic phosphodiester.<ref>PMID:20884784</ref> <ref>PMID:19141480</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==See Also==
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*[[Endonuclease|Endonuclease]]
== References ==
== References ==
<references/>
<references/>

Revision as of 19:01, 25 December 2014

Crystal structure of Cas6 in Pyrococcus furiosus

3i4h, resolution 2.25Å

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