2vsz

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 5: Line 5:
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vsz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vsz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vsz RCSB], [http://www.ebi.ac.uk/pdbsum/2vsz PDBsum]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vsz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vsz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vsz RCSB], [http://www.ebi.ac.uk/pdbsum/2vsz PDBsum]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/ELMO1_HUMAN ELMO1_HUMAN]] Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.<ref>PMID:11595183</ref> <ref>PMID:12134158</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 28: Line 30:
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Barford, D.]]
+
[[Category: Barford, D]]
-
[[Category: Cote, J F.]]
+
[[Category: Cote, J F]]
-
[[Category: Komander, D.]]
+
[[Category: Komander, D]]
-
[[Category: Patel, M.]]
+
[[Category: Patel, M]]
[[Category: Apoptosis]]
[[Category: Apoptosis]]
[[Category: Dock180]]
[[Category: Dock180]]

Revision as of 19:07, 25 December 2014

CRYSTAL STRUCTURE OF THE ELMO1 PH DOMAIN

2vsz, resolution 2.30Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools