1f2k

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1f2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f2k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1f2k RCSB], [http://www.ebi.ac.uk/pdbsum/1f2k PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1f2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f2k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1f2k RCSB], [http://www.ebi.ac.uk/pdbsum/1f2k PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PROF2_ACACA PROF2_ACACA]] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 19:21, 25 December 2014

CRYSTAL STRUCTURE OF ACANTHAMOEBA CASTELLANII PROFILIN II, CUBIC CRYSTAL FORM

1f2k, resolution 2.30Å

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