2f24

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2f24]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F24 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F24 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2f24]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F24 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F24 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1snt|1snt]], [[1so7|1so7]], [[1vcu|1vcu]], [[2f0z|2f0z]], [[2f10|2f10]], [[2f11|2f11]], [[2f12|2f12]], [[2f13|2f13]], [[2f25|2f25]], [[2f26|2f26]], [[2f27|2f27]], [[2f28|2f28]], [[2f29|2f29]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1snt|1snt]], [[1so7|1so7]], [[1vcu|1vcu]], [[2f0z|2f0z]], [[2f10|2f10]], [[2f11|2f11]], [[2f12|2f12]], [[2f13|2f13]], [[2f25|2f25]], [[2f26|2f26]], [[2f27|2f27]], [[2f28|2f28]], [[2f29|2f29]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f24 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f24 RCSB], [http://www.ebi.ac.uk/pdbsum/2f24 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f24 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f24 RCSB], [http://www.ebi.ac.uk/pdbsum/2f24 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NEUR2_HUMAN NEUR2_HUMAN]] Hydrolyzes sialylated compounds.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Exo-alpha-sialidase]]
[[Category: Exo-alpha-sialidase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Chavas, L M.G.]]
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[[Category: Chavas, L M.G]]
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[[Category: Fusi, P.]]
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[[Category: Fusi, P]]
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[[Category: Kato, R.]]
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[[Category: Kato, R]]
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[[Category: Monti, E.]]
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[[Category: Monti, E]]
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[[Category: Tettamanti, G.]]
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[[Category: Tettamanti, G]]
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[[Category: Tringali, C.]]
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[[Category: Tringali, C]]
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[[Category: Venerando, B.]]
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[[Category: Venerando, B]]
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[[Category: Wakatsuki, S.]]
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[[Category: Wakatsuki, S]]
[[Category: Drug design]]
[[Category: Drug design]]
[[Category: Ganglioside]]
[[Category: Ganglioside]]

Revision as of 19:28, 25 December 2014

Crystal Structure of the Human Sialidase Neu2 E111Q Mutant

2f24, resolution 1.76Å

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