4pdc

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4pdc]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PDC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PDC FirstGlance]. <br>
<table><tr><td colspan='2'>[[4pdc]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PDC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PDC FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ffe|4ffe]], [[1mpu|1mpu]], [[1hyr|1hyr]], [[1jsk|1jsk]], [[1kcg|1kcg]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ffe|4ffe]], [[1mpu|1mpu]], [[1hyr|1hyr]], [[1jsk|1jsk]], [[1kcg|1kcg]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pdc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pdc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pdc RCSB], [http://www.ebi.ac.uk/pdbsum/4pdc PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pdc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pdc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pdc RCSB], [http://www.ebi.ac.uk/pdbsum/4pdc PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN]] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.
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==See Also==
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*[[NK cell receptor|NK cell receptor]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Structural genomic]]
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[[Category: Fremont, D H.]]
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[[Category: Fremont, D H]]
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[[Category: Lazear, E.]]
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[[Category: Lazear, E]]
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[[Category: Nelson, C A.]]
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[[Category: Nelson, C A]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Immune evasion]]
[[Category: Immune evasion]]
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[[Category: Orthopoxvirus]]
[[Category: Orthopoxvirus]]
[[Category: Secreted viral protein]]
[[Category: Secreted viral protein]]
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[[Category: Structural genomic]]
 

Revision as of 19:31, 25 December 2014

Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D

4pdc, resolution 1.99Å

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