3p45
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p45 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p45 RCSB], [http://www.ebi.ac.uk/pdbsum/3p45 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p45 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p45 RCSB], [http://www.ebi.ac.uk/pdbsum/3p45 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. | ||
==See Also== | ==See Also== | ||
Revision as of 19:49, 25 December 2014
Crystal structure of apo-caspase-6 at physiological pH
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